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課程名稱 |
專題研究
Research |
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開課學期 |
102-2 |
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授課對象 |
農藝學研究所 |
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授課教師 |
劉仁沛 |
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課號 |
Agron8001 |
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課程識別碼 |
621 D0060 |
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班次 |
10 |
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學分 |
2 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
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上課地點 |
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備註 |
總人數上限：3人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1022Agron8001_10_LIU |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
The objective of this course is to supervise and direct one PhD candidate on her dissertation, and to have regular weekly meetings to monitoring research progress and to write up the manuscript for submission to the SCI statistical journals. The topic of the research is "Statistical Inference for Targeted Therapy Based on Censored Data under Enrichment Design". This is a very important research topic for evaluation of tareged drugs. This is because the accuracy of the diagnostic devices for the molecular targets is not 100%. |
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課程目標 |
(1) Try to use the EM algorithm to account for the inaccuracy of diagnsotic device and uncertainty of estimated positive predictive value for inference of treatment effect under exponential distribution and Cox proportional model.
(2) Conduct simulation studies to evaluate the proposed methods in terms of bias, cverage probability, size and power.(3) After the completion of research work, a manuscript will be prepared and will be submitted to SCI statistical journals. |
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課程要求 |
(1) Complete derivation of statistical methods
(2) Complete the simulation studies
(3) Complete the manuscripts
(4) Submit the manuscripts to SCI journals |
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預期每週課後學習時數 |
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Office Hours |
每週一 08:00~09:00 |
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指定閱讀 |
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參考書目 |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
submission of manuscript |
10% |
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2. |
complete manuscript |
10% |
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3. |
complete simulation |
40% |
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4. |
complete derivation |
40% |
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